. Author manuscript; available in PMC: 2011 Oct 19.

Published in final edited form as: Environ Mol Mutagen. 2009 Jul;50(6):460–472. doi: 10.1002/em.20482

TABLE V.

Average Infectious Virus Yield Reduction Per Unit Dose of WR1065 in Adenovirus or Influenza-Infected Cells

Virus tested	Cell type used in the plaque reduction assay	Dose of WR1065 administered (μM)	Average # of PFUs reduced by exposure to WR1065 (×10⁶)	PFUs reduced per unit dose of WR1065 (×10⁶)
AD7-P	A549	0	(3.5)^a	NA
		10	1.65	0.17
		33	2.65	0.08
		100	2.35	0.02
AD5-P	A549	0	(8.9)^a	NA
		10	2.7	0.27
		33	3.2	0.10
		100	6.7	0.07
AD4-P	A549	0	(1,900)^a	NA
		33	480	14.55
		100	920	9.20
Influenza A/HKx31 (H3N2)	MDCK	0	(66.3)^a	NA
		10	7	0.70
		33	9.3	0.28
		100	18.3	0.18
Influenza B/Lee/40	MDCK	0	(26.7)^a	NA
		10	2.7	0.27
		33	6.4	0.19
		100	8.1	0.08

Average PFUs in vehicle-exposed cells.

NA, not applicable.