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Blockade of myocardial STAT3 activation in SDF-1-improved myocardial function following I/R. A: myocardial levels of phosphor-STAT3 (p-STAT3) and total-STAT3 (T-STAT3) are analyzed by Western blot after administration of STAT3 inhibitor Stattic in response to acute I/R. B−D: inhibition of STAT3 activation abolishes SDF-1-improved myocardial function following I/R. Results are means ± SE; n = 5–7/group.
