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Coronary resistance in WT, SIRT1+/−, and SIRT1+++ hearts
| WT | SIRT1+/− | SIRT1+++ | |
|---|---|---|---|
| Before ischemia | 32 ± 3 | 40 ± 4 | 33 ± 3 |
| 60 min of reperfusion | 38 ± 4* | 41 ± 7 | 35 ± 4 |
Values are means ± SE; n = 3. Coronary resistance (in mmHg · ml−1 · min−1) was calculated as the ratio of coronary root pressure (in mmHg) to coronary flow (in ml/min).
P < 0.05 vs. WT before ischemia (by t-test).
