Fig. 3.

Group data showing the sympathoexcitatory responses to ICV misoprostol (0.5 nmol; A) and ICV sulprostone (0.5 nmol; B) were significantly diminished by pretreatment with the EP₃ receptor antagonist L-798106, partially reduced by pretreatment with the EP₄ receptor antagonist L-161982, and unaffected by pretreatment with the EP₁ receptor antagonist SC-19220. Antagonist doses are same as in Fig. 2. Arrows indicate time of misoprostol and sulprostone injections. n, Number of interventions. *P < 0.05 vs. Veh; †P < 0.05 vs. Veh + misoprostol or Veh + sulprostone.