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Effects of the Ca2+/calmodulin-dependent protein kinase inhibitor KN-93. Pooled data (means ± SE) of 3 mM [Ca2+]o ± KN-93 on maximal steady-state Ca2+ transient amplitude (A) and corresponding RT50 (C). Pooled data (means ± SE) of ISO ± KN-93 on maximal steady-state Ca2+ transient amplitude (B) and corresponding RT50 (D) (−KN-93: n = 21 cells/10 hearts, +KN-93: n = 15 cells/4 hearts).
