Table 1.
Muscle Weight, mg |
Muscle Weight/Body Weight, mg/g |
L0, mm |
Cross-Sectional Area, mm2 |
||||||
---|---|---|---|---|---|---|---|---|---|
Animal | Body Weight, g | EDL | Soleus | EDL | Soleus | EDL | Soleus | EDL | Soleus |
WT | 35.9 ± 1.3 (8) | 10.7 ± 0.3 (9) | 10.5 ± 0.2 (9) | 0.30 ± 0.01 | 0.29 ± 0.01 | 11.6 ± 0.4 | 12.0 ± 0.3 | 0.88 ± 0.04 | 0.83 ± 0.03 |
Tg+ | 28.5 ± 0.6* (7) | 9.3 ± 0.3† (7) | 9.3 ± 0.5† (7) | 0.31 ± 0.01 | 0.32 ± 0.02 | 10.4 ± 0.3 | 10.1 ± 0.2 | 0.84 ± 0.05 | 0.87 ± 0.05 |
Values are means ± SE; number in parenthesis are the number of animals analyzed (for body wt) or number of muscles analyzed (for muscle wt). L0, muscle optimal length; EDL, extensor digitorum longus; WT, wild type; Tg+, transgenic mouse model that overexpresses TNF-α in the lung.
P < 0.05 vs. WT, Student's t-test;
P < 0.05 vs. WT, one-way ANOVA.