Table 2.
LZR | OZR | O-P | O-T | O-SQ | O-LN | O-PT | O-PSQ | O-PLN | O-TLN | O-TSQ | O-PTSQ | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1A | ||||||||||||
ID | 94 ± 4 | 85 ± 6 | 92 ± 3 | 87 ± 6 | 88 ± 5 | 84 ± 6 | 93 ± 3 | 93 ± 4 | 90 ± 4 | 86 ± 3 | 86 ± 4 | 93 ± 3 |
VRBC | 56 ± 5 | 46 ± 6 | 48 ± 5 | 45 ± 6 | 49 ± 7 | 38 ± 6* | 52 ± 6 | 53 ± 5 | 46 ± 5 | 48 ± 5 | 48 ± 4 | 53 ± 5 |
Q | 245 ± 14 | 165 ± 20* | 200 ± 15 | 169 ± 14* | 186 ± 9* | 134 ± 15* | 219 ± 6† | 224 ± 14† | 183 ± 13* | 175 ± 13* | 176 ± 14* | 227 ± 17† |
2A | ||||||||||||
ID | 75 ± 4 | 66 ± 5 | 72 ± 3 | 69 ± 6 | 68 ± 6 | 64 ± 5 | 73 ± 4 | 74 ± 4 | 71 ± 5 | 67 ± 6 | 69 ± 5 | 74 ± 4 |
VRBC | 40 ± 6 | 35 ± 5 | 40 ± 5 | 36 ± 6 | 36 ± 5 | 32 ± 4 | 39 ± 5 | 39 ± 4 | 36 ± 6 | 37 ± 5 | 38 ± 6 | 40 ± 4 |
Q | 112 ± 10 | 74 ± 12* | 100 ± 9 | 84 ± 9* | 82 ± 5* | 65 ± 6* | 102 ± 5 | 105 ± 8 | 89 ± 9 | 82 ± 11* | 89 ± 12 | 108 ± 6† |
3A | ||||||||||||
ID | 53 ± 4 | 48 ± 7 | 50 ± 5 | 53 ± 6 | 53 ± 5 | 47 ± 6 | 52 ± 5 | 53 ± 5 | 48 ± 5 | 52 ± 5 | 53 ± 6 | 53 ± 5 |
VRBC | 20 ± 4 | 14 ± 3 | 17 ± 4 | 14 ± 3 | 14 ± 3 | 12 ± 3 | 18 ± 3 | 18 ± 4 | 15 ± 4 | 12 ± 3 | 14 ± 4 | 20 ± 2 |
Q | 28 ± 4 | 16 ± 4* | 21 ± 3 | 19 ± 4 | 19 ± 3 | 13 ± 3* | 24 ± 5 | 25 ± 5 | 17 ± 3 | 16 ± 3 | 19 ± 4 | 28 ± 4* |
4A | ||||||||||||
ID | 36 ± 4 | 30 ± 3 | 31 ± 3 | 33 ± 5 | 32 ± 4 | 28 ± 3 | 34 ± 5 | 34 ± 4 | 29 ± 4 | 32 ± 5 | 35 ± 4 | 35 ± 3 |
VRBC | 12 ± 3 | 8 ± 2 | 12 ± 3 | 9 ± 2 | 10 ± 3 | 8 ± 2 | 11 ± 2 | 12 ± 2 | 8 ± 2 | 9 ± 2 | 9 ± 2 | 12 ± 2 |
Q | 7.8 ± 1.9 | 3.7 ± 1.5 | 5.5 ± 1.7 | 4.7 ± 1.1 | 4.8 ± 1.3 | 3.1 ± 0.8* | 6.1 ± 1.6 | 6.6 ± 1.3 | 3.5 ± 0.9 | 4.3 ± 1.2 | 5.5 ± 1.4 | 7.2 ± 1.6 |
5A | ||||||||||||
ID | 21 ± 3 | 18 ± 3 | 18 ± 2 | 20 ± 3 | 19 ± 3 | 18 ± 3 | 19 ± 2 | 20 ± 3 | 18 ± 2 | 19 ± 3 | 19 ± 2 | 20 ± 2 |
VRBC | 7 ± 1 | 4 ± 1 | 5 ± 2 | 4 ± 1 | 4 ± 1 | 3 ± 1 | 6 ± 2 | 7 ± 2 | 5 ± 2 | 5 ± 2 | 5 ± 1 | 7 ± 1 |
Q | 1.5 ± 0.3 | 0.7 ± 0.2* | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.7 ± 0.2* | 0.5 ± 0.2* | 1.1 ± 0.3 | 1.3 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.3 | 1.4 ± 0.3 |
Data are presented as means ± SE. Data are presented for arteriolar inner diameter (ID; μm), centerline erythrocyte velocity (VRBC; mm/s), and volume perfusion within the arteriole (Q; nl/s).
P < 0.05 vs. LZR;
P < 0.05 vs. OZR. P denotes treatment with phentolamine; T denotes treatment with TEMPOL; SQ denotes treatment with SQ-29548; LN denotes treatment with l-NAME; with combinations representing treatment with multiple agents.