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. 2011 Oct 19;6(10):e26581. doi: 10.1371/journal.pone.0026581

Figure 10. Acute βAR stimulation in vivo induces an increase in the phophorylation of FOXO1 and FOXO3a.

Figure 10

C57BL/6 mice were treated with vehicle control or isoproterenol (ISO, 1.25 mg/kg, i.p.) for 30 min. Representative Western blot analyses were performed on left ventricular lysates with antibodies against phospho-FOXO1(Thr24)/FOXO3a(Thr32), phospho-FOXO3a (Ser318/321, Ser253), total FOXO1 and total FOXO3a. The bar graphs show the densitometric scanning results from two seperate experiments (n = 6). Data are normalized with individual total protein levels. *, p<0.05 versus vehicle control.