Table 2. Density of NOGO-A immunopositive mature oligodendrocytes and Mac-3 immunopositive microglia and macrophages in the midline of corpus callosum.
| NOGO-A | Mac-3 | ||||||
| Control | 6 weeks cuprizone exposure | 2 weeks after ending cuprizone exposure | Control | 6 weeks cuprizone exposure | 2 weeks after ending cuprizone exposure | ||
| Diet | <50 IU/kg | 61.0 (11.8) | 14.8 (10.0)* | 71.0 (7.8) | 3.2 (2.3) | 249.7 (116.2) | 69.6 (19.0) |
| 500 IU/kg | 57.8 (12.4) | 6.0 (5.8)* | 60.2 (15.9) | 1.2 (1.0) | 270.0 (47.9) | 45.0 (20.4) | |
| 6200 IU/kg | 62.3 (17.3) | 16.2 (6.2)* | 72.7 (9.9) | 2.3 (2.3) | 95.3 (85.4)** | 32.2 (10.4) | |
| 12500 IU/kg | 69.5 (12.0) | 11.6 (8.0)* | 62.3 (7.9) | 2.8 (3.0) | 107.1 (53.1)** | 71.5 (34.6) | |
Cell counts are provided as mean (± SD) number of cells per 0.0625 mm2.
*p<0.005.
**p = 0.001.