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. 2011 Oct 20;7(10):e1002240. doi: 10.1371/journal.pcbi.1002240

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Venet et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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In plots A–C the NKI cohort was split into two groups using a signature of post-prandial laughter (panel A), localization of skin fibroblasts (panel B), social defeat in mice (panel C). In panels A–C, the fraction of patients alive (overall survival, OS) is shown as a function of time for both groups. Hazard ratios (HR) between groups and their associated p-values are given in bottom-left corners. Panel D depicts p-values for association with outcome for all MSigDB c2 signatures and random signatures of identical size as MSigDB c2 signatures.