Table 1. Top tissues and health states containing ultra-edited ESTs.

Tissue	Number of ESTs	Enrichmenta	Health state	Number of ESTs	Enrichmenta
Liver	312	12.98	Normal	563	1.57
Brain	118	0.97	Lung tumor	13	0.73
Lung	33	0.89	Glioma	9	0.78
Thymus	31	3.74	Soft tissue/muscle tissue tumor	9	0.69
Eye	21	0.93	Non-neoplasia	8	0.72
Muscle	20	1.63	Head and neck tumor	8	0.37
Prostate	20	0.65	Colorectal tumor	8	0.4
Uterus	19	0.74	Kidney tumor	6	0.61
Uncharacterized tissue	15	0.4	Gastrointestinal tumor	6	0.42
Spleen	12	2.17	Uterine tumor	6	0.57

^aThe enrichment is the number of ultra-edited ESTs from the tissue divided by the expected number, which was computed as follows. For each tissue, we calculated the ratio of the total number of ESTs in the tissue to the total number of ESTs in all tissues. The expected number of ultra-edited ESTs in a tissue is the latter ratio multiplied by the total number of ultra-edited ESTs. Enrichment of health states was similarly calculated.