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. 2011 Oct 20;7(10):e1002343. doi: 10.1371/journal.pgen.1002343

Table 2. Genetic terms significantly associated with variation in immunological parameters.

Genetic term Response Model d.f Terma Coefficient (s.e.) p-value
Il1b Il1b expression Additive 4 GAC 0.11 (0.17) 0.008
GAT 0.62 (0.20)
AAC −0.15 (0.22)
GGT −0.02 (0.76)
Gata3 96 h expression Heterozygosity 1 Heterozygote −1.08 (0.52) 0.040
Il2 Il10 expression Heterozygosity 1 Heterozygote −0.42 (0.20) 0.037
Il12b Il1b expression Additiveb 2 CC 0.47 (0.30) 0.003
GT 1.56 (0.49)
Il2 expression Heterozygosityc 1 Heterozygote −1.15 (0.37) 0.002
a

Under an additive model, listed haplotypes were compared against the most common haplotype at that locus; under a heterozygosity model, values of heterozygotes were compared against homozygotes (see text).

b

Also significant under a heterozygosity model (p = 0.04).

c

Also significant under an additive model (p = 0.007).