Table 2. Genetic terms significantly associated with variation in immunological parameters.
Genetic term | Response | Model | d.f | Terma | Coefficient (s.e.) | p-value |
Il1b | Il1b expression | Additive | 4 | GAC | 0.11 (0.17) | 0.008 |
GAT | 0.62 (0.20) | |||||
AAC | −0.15 (0.22) | |||||
GGT | −0.02 (0.76) | |||||
Gata3 96 h expression | Heterozygosity | 1 | Heterozygote | −1.08 (0.52) | 0.040 | |
Il2 | Il10 expression | Heterozygosity | 1 | Heterozygote | −0.42 (0.20) | 0.037 |
Il12b | Il1b expression | Additiveb | 2 | CC | 0.47 (0.30) | 0.003 |
GT | 1.56 (0.49) | |||||
Il2 expression | Heterozygosityc | 1 | Heterozygote | −1.15 (0.37) | 0.002 |
Under an additive model, listed haplotypes were compared against the most common haplotype at that locus; under a heterozygosity model, values of heterozygotes were compared against homozygotes (see text).
Also significant under a heterozygosity model (p = 0.04).
Also significant under an additive model (p = 0.007).