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. 2011 Oct 20;7(10):e1002343. doi: 10.1371/journal.pgen.1002343

Table 5. Comparison of effect sizes for genetic versus intrinsic terms in pathogen resistance.

Genetic term Response Dataset a Modelb d.f. Coefficient Sex Body weightc Eye lens weightc
Il1b Tick infection CS Heterozygosity 1 0.91 0.35 1.11 −0.74
Bartonella infection Long. Heterozygosity 1 −0.61 n.s. n.s. 0.32
Flea infection Long. Additive 4 −0.25 to 1.27 0.72 −0.04 n.d.
Il2 Nematode infection CS Additive 2 −0.03 to 0.70 0.82 n.s. n.s.
Cestode burden CS Heterozygosity 1 −0.45 −1.61 0.16 −0.33
Flea burden CS Heterozygosity 1 −0.27 n.s. 0.53 n.s.
Tick infection Long. Additive 2 −0.66 to 0.21 n.s. 0.15 n.d.
Tick burden CS Heterozygosity 1 0.58 n.s. 2.68 n.d.
Babesia infection Long. Heterozygosity 1 0.66 −0.70 0.32 n.d.
Bartonella infection Long. Heterozygosity 1 −0.61 −0.22 −0.47 n.d.
Il12b Nematode infection CS Additive 2 0.42 to 1.42 0.82 n.s. n.s.
Babesia infection Long. Additive 2 0.26 to 1.02 −0.70 0.32 n.d.
Slc11a1 Flea burden CS Heterozygosity 1 −0.28 n.s. 0.53 n.s.
Tick burden CS Heterozygosity 1 0.67 n.s. 2.68 n.d.
Tlr2 Cestode burden CS Heterozygosity 1 0.37 −1.61 0.16 −0.33
Tnf Cestode infection CS Additive 1 −0.68 0.88 0.46 −0.70
a

Refers to cross-sectional (CS) or longitudinal (Long.) studies, which utilized GLMs and GLMMS, respectively, for analyses (see text).

b

Under an additive model, the range of effect sizes for alleles is shown compared against the most common haplotype at that locus; under a heterozygosity model, values of heterozygotes were compared against homozygotes (see text).

c

Effect size shown for comparative purposes based on the interquartile range for females within a single season (Spring 2008).