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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Bioorg Med Chem. 2011 Aug 27;19(21):6474–6482. doi: 10.1016/j.bmc.2011.08.053

Scheme 4.

Scheme 4

Synthesis of multivalent compounds 13, 14a–14e, and 15a–d via CuAAC.a

aThe positions of ligand attachment are presumed to be random.