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Locomotor activity, as expressed in fine movements, in rats treated with saline (Sal), methamphetamine (Ma; 0.3 mg/kg), morphine (Mor; 1.0, 5.0 or 10 mg/kg s.c.) or the combination of Ma and Mor. Left panels = total fine movements during the first 90 minutes post-injection. Right panels = total fine movements during the second 90 minutes post-injection. *=significantly different from Sal; ^=Mor/Ma significantly different from Mor alone; †=Mor/Ma significantly different from Ma alone.
