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Locomotor activity, as expressed in fine movements, for the 210 minute time course in rats treated with saline (Sal), methamphetamine (Ma; 1.0 mg/kg), morphine (Mor; 1.0, 5.0 or 10 mg/kg s.c.) or the combination of Ma and Mor. Two-way repeated measures ANOVA for the time course showed a significant effect of treatment, time and interaction at all three dose combinations (p≤0.01).
