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Genotoxicity to intestinal epithelial cells. A, B. DNA damage by alkaline comet assay without (black bars) and with hOgg1 incubation (white bars), and by γ-H2AX immunostaining, respectively, in intestinal epithelial cells from small and large intestine of IL-10−/− versus wildtype mice. LI: large intestine, SI: small intestine, *: p<0.05, **: p<0.01 by one way ANOVA with Dunn’s multiple comparison test. Error bars represent SEM of 5–7 mice per group.
