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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Circ Cardiovasc Genet. 2011 Aug 12;4(5):500–509. doi: 10.1161/CIRCGENETICS.111.960633

Figure 3.

Figure 3

Biophysical Properties of Rescued Currents are Altered A. Conductance was similar for WT, rescued channels (R282H+R558-40aa and R282H+R558-20aa), and WT channels treated with the R558-containing peptide (WT+R558-40aa). B. Steady-State Inactivation of rescued currents (closed symbols) was significantly shifted toward depolarized potentials. C. Recovery from Inactivation. The time constants of recovery from inactivation were significantly faster for rescued channels. D. Time Constant of Inactivation. Inactivation of R282H+R558-20aa channels (n=9) was significantly slower than WT channels (n=7). R282H+R558-40aa channels (n=5) and WT+R558-40aa channels (n=9) behaved similarly to WT. *P<0.05 compared to WT.