Table 3. Ligand selectivitiy for the dopamine D3, D2, and the β2 adrenergic receptor.
Receptor Affinity (Ki, μM)a | |||
---|---|---|---|
| |||
Dopamine | Adrenergic | ||
| |||
# | D3 | D2 | β2 |
2 | 3.1 | 1.3 | >10 |
3 | 1.6 | >10 | >10 |
4 | 0.2 | 0.4 | >10 |
5 | 1.8 | 0.4 | >10 |
6 | 1.3 | 4.5 | >10 |
7 | 0.5 | >10 | >10 |
28 | 0.3 | 0.9 | n.d. |
29 | 2.2 | 3.9 | n.d. |
30 | 0.3 | >10 | n.d. |
31 | 1.6 | >10 | n.d. |
32 | 3.0 | 3.8 | n.d. |
n.d.; Not determined
The uncertainty in each measured Ki is ±30%.