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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Alcohol Clin Exp Res. 2011 Jun 2;35(11):2008–2018. doi: 10.1111/j.1530-0277.2011.01552.x

Table 1.

Locations and minor allele frequencies of genotyped SNPs.

Minor Allele Frequencies
SNP Chromosome
Position		 Gene SNP
Type/Location		 Alleles1 Indians Caucasians2 African-
Americans2
rs1230155 99989258 ADH5 intergenic A/G 0.200 0.345 0.318
rs7683802 99995137 ADH5 intron 7 T/G 0.063 0.102 0.107
rs4699699 99997178 ADH5 intron 6 C/G 0.06 0.108 0.071
rs4699700 99998334 ADH5 intron 4 A/G 0.074 0.148 0.261
rs1154412 100001246 ADH5 intron 4 C/T 0.135 0.19 0.031
rs7683704 100004225 ADH5 intron 2 C/T 0.07 0.108 0.268
rs1154401 100009737 ADH5 intron 1 C/G 0.213 0.355 0.364
rs1154400 100010009 ADH5 5' end T/C 0.145 0.328 0.341
rs7667261 100011299 ADH5 5' end C/G 0.015 0.044 0.212
rs2602846* 100025150 ADH5/ADH4 intergenic A/T 0.133 0.299 0.123
rs2602866 100034996 ADH5/ADH4 intergenic G/A 0.13 0.295 0.135
rs1042365* 100045499 ADH4 exon 9 C/A 0.136 0.294 0.138
rs1042364* 100045573 ADH4 exon 9 G/A 0.096 0.294 0.138
rs29001229
(DWSHpy188I)* 		100046822 ADH4 IVS8 T/C 0.136 0.295 0.135
rs1126672* 100047811 ADH4 exon 8 coding-
synon		 C/T 0.133 0.305 0.165
rs1126671 100048413 ADH4 exon 7 G/A 0.208 0.319 0.223
rs1126670 100052732 ADH4 exon 6 T/G 0.21 0.315 0.217
rs7694646* 100059731 ADH4 intron 4 T/A 0.152 0.294 0.135
rs4699714* 100060537 ADH4 intron 4 A/G 0.135 0.304 0.119
rs4148886 100064648 ADH4 intron 1 A/G 0.464 0.242 0.49
rs1800759* 100065508 ADH4 5'UTR A/C3 0.428 0.581 0.233
rs3762894* 100066083 ADH4 5'UTR T/C 0.108 0.166 0.225
rs4699718* 100067790 ADH4/ADH6 intergenic G/A 0.136 0.298 0.122
rs1984362* 100070972 ADH4/ADH6 intergenic C/T 0.094 0.294 0.094
rs4147545 100128752 ADH6 intron 6 G/A3 0.438 0.658 0.453
rs3857224 100129684 ADH6 intron 6 T/C3 0.469 0.667 0.453
rs6833176 100131162 ADH6 intron 5 C/G 0.397 0.461 0.186
rs9307238 100136181 ADH6 intron 2 G/A 0.409 0.488 0.359
rs1230026 100185618 ADH6/ADH1A intergenic A/C 0.235 0.223 0.074
rs1618572 100195120 ADH6/ADH1A intergenic C/G 0.241 0.224 0.056
rs2866151* 100198511 ADH1A intron 8 A/T 0.425 0.456 0.233
rs3819197 100200508 ADH1A intron 8 C/T 0.819 0.749 0.725
rs1229976 100202077 ADH1A intron 6 T/C 0.242 0.224 0.073
rs1229970 100204379 ADH1A intron 5 G/T 0.227 0.221 0.056
rs6828526 100205886 ADH1A exon 4 G/A 0.000 0.001 0.009
rs1229967 100207577 ADH1A intron 3 G/C 0.241 0.223 0.055
rs3805325 100211398 ADH1A intron 1 T/C 0.282 0.078 0.128
rs4147531* 100212196 ADH1A 5'UTR C/T 0.429 0.457 0.233
rs1229966 100213432 ADH1A 5' end T/C4 0.328 0.346 0.605
rs1826909* 100217742 ADH1A/1B intergenic C/T 0.146 0.373 0.171
rs1042026 100228465 ADH1B 3' UTR A/G 0.171 0.306 0.132
rs2066702* 100229016 ADH1B exon 9 coding-
nonsyn		 C/T 0.041 0.004 0.165
rs1789883 100236374 ADH1B intron 5 G/A 0.118 0.027 0.015
rs2066701 100238412 ADH1B intron 3 C/T 0.173 0.304 0.122
rs1229984* 100239318 ADH1B coding-nonsyn G/A 0.028 0.034 0.019
rs1229983 100240001 ADH1B exon 2 T/C 0.110 0.024 0.044
rs1353621 100241574 ADH1B intron 1 A/G 0.142 0.370 0.123
rs1159918* 100243008 ADH1B 3'UTR T/G3 0.292 0.652 0.355
rs1229982* 100243931 ADH1B 3'UTR G/T 0.273 0.22 0.443
rs1614972 100258154 ADH1C intron 8 C/T 0.147 0.330 0.493
rs35719513
(P351T)		 100260782 ADH1C exon 8 C/A 0.079 0.005 0
rs698* 100260788 ADH1C exon 8 coding-
nonsyn		 A/G 0.403 0.389 0.185
rs1789903 100262040 ADH1C intron 6 C/G 0.410 0.389 0.169
rs1693482* 100263964 ADH1C exon 6 coding-
nonsyn		 C/T 0.391 0.383 0.178
rs1693426 100266329 ADH1C intron 4 A/G 0.409 0.387 0.171
rs1789915 100266370 ADH1C exon 4 A/G 0.197 0.261 0.144
rs3133158 100270611 ADH1C intron 1 C/G 0.204 0.285 0.160
rs1789924 100274285 ADH1C 5' end C/T 0.414 0.389 0.179
rs1229849 100284684 ADH1C/ADH7 intergenic T/A 0.197 0.280 0.147
rs283406 100298470 ADH1C/ADH7 intergenic C/T 0.033 0.079 0.082
rs284794 100323028 ADH1C/ADH7 intergenic A/T 0.055 0.109 0.157
rs284786* 100333976 ADH7 3'UTR A/T 0.294 0.272 0.459
rs284779* 100338260 ADH7 intron 7 C/G 0.392 0.458 0.170
rs2584464 100339048 ADH7 intron 7 A/G5 0.416 0.516 0.678
rs971074 100341860 ADH7 exon 6 G/A 0.073 0.104 0.177
rs1154468 100354256 ADH7 intron 1 A/T 0.488 0.328 0.161
SBP2 100356465 ADH7 5' end A/G 0.102 0.130 0.051
rs1154476 100360726 ADH7 intergenic G/A 0.497 0.384 0.138
rs894363 100376845 ADH7 intergenic C/T 0.497 0.379 0.165

Notes:

*

Indicates SNPs that were genotyped in the full sample,

1

Alleles indicated are from the + strand and are ordered major/minor based on prevalence estimates from the present sample,

2

Allele frequencies cited from Edenberg et al. (2006),

3

The designated 'minor' allele in the Native American sample was observed at a frequency >0.50 among the European-American sample,

4

The designated 'minor' allele in the Native American sample was observed at a frequency >0.50 among the African-American sample,

5

The designated 'minor' allele in the Native American sample was observed at a frequency >0.50 among the European-American and African-American samples