Figure 5. Antagonism of the CB₁ receptor within distinct amygdalar nuclei differentially affects stress-induced increases in corticosterone secretion.

Infusion of the CB₁ receptor antagonist AM251 (2.5 μg) into the basolateral nucleus of the amygdala (BLA) significantly increased corticosterone secretion, while there was no effect of AM251 infusion into the central nucleus of the amygdala (CeA) or the medial amygdala (MeA). Values denoted are means ± SEM. * denotes significant differences (p < .05).