Table 3. The effect of infusion of the FAAH inhibitor URB597 into the central nucleus and the medial nucleus of the amygdala on stress-induced corticosterone secretion.
Infusion of the FAAH inhibitor URB597 (0.1 and 1 μg) into the central nucleus of the amygdala (CeA) and the medial nucleus of the amygdala (MeA) prior to 30 min restraint stress had no effect on the increase in corticosterone secretion following stress. Values denoted are means ± SEM. For all treatment conditions, n = 4-5.
Serum Corticosterone (ng/ml) | |
---|---|
CeA | |
Basal | 43.1 +/- 10.1 |
Stress | 401.1 +/- 85.5 |
Stress + 0.1 μg URB597 | 385.8 +/- 34.8 |
Stress + 1 μg URB597 | 410.1 +/- 52.7 |
MeA | |
Basal | 49.3 +/- 6.1 |
Stress | 443.5 +/- 18.4 |
Stress + 0.1 μg URB597 | 427.1 +/- 33.6 |
Stress + 1 μg URB597 | 446.8 +/- 30.3 |