Table 1. Subject demographics and neuropsychiatric characteristics for the ADNI sample.
The mean ± s.d. is shown for the following variables: age, education, BMI, MMSE, and sum-of-boxes CDR.
| AD (n=188) | MCI (n=399) | |
|---|---|---|
| Age | 75.4±7.5* | 74.8±7.4* |
| Sex (Male) | 99 | 257 |
| Ethnicity: White | 176 | 373 |
| Black | 8 | 15 |
| Other | 4 | 11 |
| Education (>high school) | 69.7% | 80.2% |
| Presence of ApoE4 | 67.0%** | 54.6%** |
| BMI | 25.5±3.9 | 26.1±4.0 |
| MMSE | 23.3±2.0 | 27.0±1.8 |
| Sum-of-boxes CDR | 4.4±1.6 | 1.6±0.9 |
*
An ANOVA was performed on the variable age only to determine whether the mean age differed significantly between ADNI and CHS groups. The average age was different between ADNI and CHS groups for the AD patients (F1,222 =24.5; P=1.468 × 10−6), and for the MCI patients (F1,474=32.2; P=2.404 × 10−8).
**
A chi-squared test was performed for the categorical variable, presence of ApoE4; the subscript indicates the number of degrees of freedom. The incidence of the ApoE4 allele was different between ADNI and CHS groups in AD patients (χ21 = 18.8; P =1.456 × 10−5) and MCI patients (χ21=16; P =6.5 × 10−5).