TABLE 1.

The Relationship Between the MRI Subregional Volumes and the Apathy Evaluation Scales Scores, Controlling for Diagnosis, Age, and Sex

Subregions	Total AES			AES Cognitive			AES Behavioral			AES Emotional
	β	Standard error	p value	β	Standard error	p value	β	Standard error	p value	β	Standard error	p value
Right OFC gray	−725.23	753.52	0.34	−484.30	429.18	0.26	−404.75	245.26	0.10	4.38	155.96	0.98
Right CG gray	2066.76	912.29	0.03	336.15	519.61	0.52	1004.53	296.94	0.001a	262.04	188.83	0.17
Left OFC gray	−520.09	790.08	0.51	−698.53	437.76	0.12	13.34	268.86	0.96	−19.87	161.16	0.90
Left CG gray	963.36	862.82	0.27	58.32	478.06	0.90	578.88	293.61	0.05	−64.23	175.99	0.72
Right OFC white	−134.19	1170.13	0.91	−424.37	643.00	0.51	−154.23	406.59	0.71	192.51	234.55	0.42
Right CG white	459.38	2320.49	0.84	−415.57	1275.14	0.75	387.47	806.32	0.63	21.58	465.14	0.96
Left OFC white	216.44	1001.07	0.83	−103.51	527.75	0.85	110.98	342.02	0.75	59.88	197.79	0.76
Left CG white	762.23	1712.13	0.66	−173.15	902.61	0.85	516.18	584.95	0.38	138.95	338.28	0.68

Notes: The criterion value for multiple comparisons for all of coefficients is p <0.002, for an overall p value of 0.05.

OFC: orbital frontal cortex; CG: cingulate gyrus; gray: gray matter volume; white: white matter volume; AES: Apathy Evaluation Scale.

^aThe p values are from Student’s t-tests of the regression coefficients using multivariate models with df = 61.