Table 1.

atRA concentrations (pmol/g) in mouse tissues after 1-month feeding a liquid diet ± ethanol.

Diet	liver	serum	testis	kidney	Hp	Cx	Ob	Cb	St	Th
control	5.6 ± 0.4	2.2 ± 0.4	8.3 ± 0.4	3 ± 0.3	23 ± 3.6	13. 9 ± 1.5	77 ± 21	55 ± 4	78 ± 33	81 ± 6
ethanol	6.2 ± 0.9	24 ± 2*	14 ± 0.8*	3.3 ± 0.2	511 ± 253*	37.5 ± 10*	79 ± 13	52 ± 7	90 ± 33	60 ± 10

Data are means ± SE. Mice were fed liquid diets. The “ethanol” diet contained 6.5% ethanol. atRA concentrations were quantified by LC/MS/MS.

Abbreviations: Hp, hippocampus; Cx, cortex; Ob, olfactory bulb; Cb, cerebellum; St, striatum; Th, Thalamus.

P values for serum, testis, hippocampus and cortex were <0.0001, <0.0002, ~0.02 and <0.05, respectively.