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Bone marrow biopsy in a systemic mastocytosis patient. A: Diffuse mast cell (MC) infiltrate (Hematoxylin-eosin, × 10); B: The dense infiltrate is represented by MCs, whose detection is increased by positive immunohistochemical marker CD117; C: The dense infiltrate is represented by MCs, whose detection is increased by positive immunohistochemical marker CD25.
