Figure 2.

Weighted Gene Co-expression Network Analysis (WGNCA) for cortex (A), hypothalamus (B), and thalamus (C). Along the x- and y-axes are transcripts ordered according to hierarchical clustering using an adjacency metric. Axis color bars represent assignment of transcripts to modules of co-expressed genes, where the color name is used as the module identifier. The circled modules were found to be significantly enriched for candidate causal sleep genes (CCSGs) and are expanded in the blown-up squares designated as plum (A), deeppink and maroon (B), and deeppink (C). For this analysis, genes were filtered such that the top 50% of most varying transcripts were included.