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Expression and activation of Rac1 are significantly increased in ZDF rat islets. Total Rac1 expression in islets from the ZLC and the ZDF rats was determined by Western blotting (A) and quantitated densitometrically (B). C: The degree of Rac1 activation was quantitated by the GLISA method. D: Data are expressed as percent change in Rac1 activation over total Rac1 and are mean ± SEM (error bars) from islets from six rats in each group. *P < 0.05 vs. ZLC rat islets.
