TABLE 1.
Phylogenetic analysis of the taxa enriched or depleted in prebiotic-fed mice using pyrosequencing
| Abundance (percent of total sequences) |
||||
|---|---|---|---|---|
| Rank | RDP classification | Ob-CT | Ob-Pre | Change (%)* |
| Subclass | Actinobacteria; Actinobacteria; Actinobacteridae | 0.006 ± 0.004 | 0.12 ± 0.05 | 1,971 |
| Order | Actinobacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales | 0 ± 0 | 0.12 ± 0.05 | Ob-Pre |
| Family | Actinobacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales; Bifidobacteriaceae | 0 ± 0 | 0.12 ± 0.05 | Ob-Pre |
| Genus | Actinobacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium | 0 ± 0 | 0.12 ± 0.05 | Ob-Pre |
| Phylum | Bacteroidetes | 52 ± 3 | 64 ± 2 | 24 |
| Class | Bacteroidetes; Bacteroidia | 52 ± 3 | 64 ± 2 | 23 |
| Order | Bacteroidetes; Bacteroidia; Bacteroidales | 52 ± 3 | 64 ± 2 | 23 |
| Family | Bacteroidetes; Bacteroidia; Bacteroidales; Prevotellaceae | 2.6 ± 0.5 | 4.1 ± 0.5 | 55 |
| Genus | Bacteroidetes; Bacteroidia; Bacteroidales; Prevotellaceae; Prevotella | 1.4 ± 0.2 | 2.4 ± 0.2 | 73 |
| Genus | Bacteroidetes; Bacteroidia; Bacteroidales; Porphyromonadaceae; Tannerella | 1.4 ± 0.2 | 1.9 ± 0.1 | 33 |
| Genus | Bacteroidetes; Bacteroidia; Bacteroidales; Porphyromonadaceae; Barnesiella | 8.5 ± 0.8 | 10.7 ± 0.6 | 26 |
| Phylum | Firmicutes | 44 ± 4 | 29 ± 2 | −33 |
| Class | Firmicutes; Clostridia; Clostridia | 42 ± 4 | 28 ± 2 | −34 |
| Order | Firmicutes; Clostridia; Clostridiales | 42 ± 4 | 27 ± 2 | −35 |
| Genus | Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Anaerofilum | 0.04 ± 0.01 | 0.003 ± 0.003 | −93 |
| Genus | Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Anaerotruncus | 1.0 ± 0.1 | 0.26 ± 0.04 | −74 |
| Genus | Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Subdoligranulum | 0.015 ± 0.007 | 0.07 ± 0.02 | 376 |
| Family | Lachnospiraceae | 33 ± 3 | 18 ± 2 | −44 |
| Genus | Firmicutes; Clostridia; Clostridiales; Lachnospiraceae; Syntrophococcus | 0.012 ± 0.005 | 0 ± 0 | Ob-CT |
| Genus | Firmicutes; Clostridia; Clostridiales; Lachnospiraceae; Marvinbryantia | 2.1 ± 0.6 | 0.8 ± 0.2 | −63 |
| Genus | Firmicutes; Clostridia; Clostridiales; Lachnospiraceae; Anaerostipes | 0.023 ± 0.008 | 0.003 ± 0.003 | −88 |
| Class | Proteobacteria; Betaproteobacteria | 0.18 ± 0.08 | 0.6 ± 0.1 | 259 |
| Order | Proteobacteria; Betaproteobacteria; Burkholderiales | 0.17 ± 0.08 | 0.6 ± 0.1 | 271 |
| Family | Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae | 0.17 ± 0.08 | 0.6 ± 0.1 | 269 |
| Genus | Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Parasutterella | 0.17 ± 0.08 | 0.6 ± 0.1 | 269 |
Data are mean ± SEM.
*P < 0.05, as determined by a two-tailed Student t test with equal variance. Ob-CT, found only in the control group; Ob-Pre, found only in prebiotic-fed mice.