Scheme 1. Synthesis of [11C]TGN-020.
(a) n-BuLi, ether, He, −70 °C, 30 min. (b) [11C]CO2 (g), −70 °C, 3 min. (c) 2-Amino-1,3,4-thiadiazole, EDC·HCl, DMF, 50 °C, 5 min.
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