Table 3.
HIV+ subjects (n = 491) |
Control subjects (n = 187) |
|||||
---|---|---|---|---|---|---|
Estimate | 95% CI | P value | Estimate | 95% CI | P value | |
Female vs. male | −3.8 | (−13.7 to 6.2) | 0.46 | 12.5 | (−2.6 to 27.5) | 0.10 |
African American vs. Caucasian | −2.4 | (−9.9 to 5.1) | 0.53 | 4.1 | (−5.0 to 13.1) | 0.37 |
Other vs. Caucasian | 0.75 | (−9.6 to 11.1) | 0.89 | |||
Age (per decade) | 9.0 | (4.4–13.5) | 0.0001 | 2.2 | (−10.3 to 14.8) | 0.72 |
Drinks | ||||||
<1 vs. none | −2.0 | (−10.6 to 6.6) | 0.65 | −1.8 | (−17.2 to 13.6) | 0.82 |
1–7 vs. none | −7.5 | (−15.2 to 0.27) | 0.059 | −0.81 | (−15.7 to 14.1) | 0.92 |
>7 vs. none | −17.6 | (−28.6 to −6.5) | 0.0019 | −0.10 | (−19.8 to 19.6) | 0.99 |
Physical activity | ||||||
2nd vs. 1st quartile | 8.4 | (−1.11 to 17.8) | 0.084 | 3.2 | (−11.6 to 18.0) | 0.67 |
3rd vs. 1st quartile | 0.64 | (−9.1 to 10.3) | 0.90 | 9.6 | (−3.3 to 22.5) | 0.14 |
4th vs. 1st quartile | −10.5 | (−18.4 to −2.7) | 0.0088 | 5.4 | (−8.4 to 19.3) | 0.44 |
Upper trunk SAT (doubling) | 13.8 | (8.9–18.6) | <0.0001 | 20.4 | (11.1–29.7) | <0.0001 |
Leg SAT (doubling) | −10.0 | (−16.3 to −3.7) | 0.0017 | −16.4 | (−30.4 to −2.5) | 0.020 |
Tenofovir use | −7.4 | (−14.1 to −0.59) | 0.033 | |||
Pertinent negatives | ||||||
VAT (doubling) | 2.1 | (−2.2 to 6.4) | 0.34 | 5.8 | (−4.4 to 15.9) | 0.25 |
VAT-to-abdominal fat ratio (doubling) | 3.4 | (−2.0 to 8.8) | 0.22 | −5.5 | (−26.1 to 15.1) | 0.59 |
Current vs. never smoking | 2.0 | (−5.8 to 9.8) | 0.61 | −1.9 | (−19.3 to 15.4) | 0.83 |
Past vs. never smoking | −1.3 | (−9.9 to 7.3) | 0.77 | −2.7 | (−15.8 to 10.3) | 0.68 |
P values in boldface denote statistical significance at P < 0.05. Unselected factors are in italics; values shown are those that would result if the factors were added back to the model individually. Those with fasting glucose ≥126 mg/dL or taking diabetes medication are excluded. Separate models were constructed for HIV-infected and control participants.