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. 2011 Oct 10;108(42):17468–17473. doi: 10.1073/pnas.1111138108

Table 1.

Date of mice used in the present study

Organ involvement at death
Max. leukemic cells in PB
BM invasion
Extramedullary tumor
Mouse no. Survival, d % Day Femoral Vertebral Expansion from BM Isolated from BM Cause of death
MYL 1 31 36.8 14 Mediastinum D
MYL 2 35 40.0 18 Abdominal cavity D
MYL 3 38 53.6 18 Lower jaw s.c. Tissue abdominal cavity D
MYL 4 42 52.9 21 Abdominal cavity axillary LN D
MYL 5 45 38.0 28 Abdominal cavity s.c. tissue D
MYL 6 48 42.6 18 + + s.c. Tissue abdominal cavity D
MYL 7 48 42.0 21 s.c. Tissue abdominal cavity, soft tissue around the testis D
MYL/G3 1 57 73.3 14 + + Sacrum B
MYL/G3 2 80 57.7 71 + + Sacrum E
MYL/G3 3 80 50.0 48 + + E
MYL/G3 4 80 54.0 71 + + Sacrum E
MYL/G3 5 80 48.0 18 + + Sacrum, right femur E
MYL/G3 6 80 48.0 68 + + E
MYL/G3 7 80 57.14 24 + + E

B, Loss of >10% body wight; D, deterioration caused by tumor; E, euthanasia; LN, lymph node; Max.: maximum.