Table 5. Genotype frequency of SNP (rs10038177) showing association with POAG.
| Genotype | Patient subgroup | Frequency in patients (n) | Frequency in controls (n) | p-value | OR (95% CI) | Relative risk (95% CI) |
|---|---|---|---|---|---|---|
| TT |
POAG |
0.47 (152) |
0.53 (161) |
0.129 |
- |
- |
| |
HTG |
0.39 (045) |
|
0.009 |
0.559 (0.362–0.864) |
0.655 (0.466–0.915) |
| |
NON-HTG |
0.52 (107) |
|
0.748 |
- |
- |
| CT |
POAG |
0.45 (145) |
0.40 (121) |
0.210 |
- |
- |
| |
HTG |
0.47 (054) |
|
0.219 |
- |
- |
| |
NON-HTG |
0.44 (091) |
|
0.365 |
- |
|
| CC |
POAG |
0.08 (26) |
0.07 (021) |
0.596 |
- |
- |
| |
HTG |
0.14 (017) |
|
0.014* |
2.306 (1.180–4.508) |
1.722 (1.077–2.487) |
| NON-HTG | 0.04 (009) | 0.223 | - | - |
*Significant observation. Comparison of the genotype frequencies of rs10038177 among 323 POAG (116 HTG cases and 207 non-HTG cases) patients and 303 controls revealed biased distribution for the CC genotype (p=0.014) portraying risk for HTG patient group.