Table 1. Demographic data for patients with chronic GVHD related dry eye (DE/cGVHD group).
| Case | Age | Gender | HSCT source | Underlying disease | Interval between HSCT and CM analysis (mo) | Interval between DE onset and CM analysis (mo) | Interval between HSCT and DE onset (mo) | DE severity level | CC | Clinically affected cGVHD organs |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
57 |
Male |
PBSC |
ML |
17 |
1 |
16 |
3 |
- |
Eye, Skin |
| 2 |
47 |
Male |
PBSC |
AML |
19 |
6 |
13 |
4 |
+ |
Eye, Skin, Mouth, Liver |
| 3 |
50 |
Male |
PBSC |
MM |
12 |
1 |
11 |
4 |
+ |
Eye, Mouth |
| 4 |
47 |
Female |
BM |
MM |
43 |
1 |
42 |
4 |
+ |
Eye, Mouth |
| 5 |
38 |
Female |
BM |
AML |
12 |
0 |
12 |
2 |
- |
Eye |
| 6 |
57 |
Male |
BM |
MDS |
14 |
N.A. |
N.A. |
3 |
+ |
Eye |
| 7 |
51 |
Male |
BM |
CML |
120 |
48 |
72 |
2 |
- |
Eye |
| 8 |
46 |
Female |
PBSC |
MM |
116 |
108 |
8 |
2 |
- |
Eye |
| 9 | 55 | Male | PBSC | AML | 25 | 17 | 8 | 4 | + | Eye, Skin |
HSCT=hematopoietic stem cell transplantation; CM=confocal microscopy; DE=dry eye; CC=cicatricial change; PBSC=peripheral blood stem cell; BM=bone marrow; ML=malignant lymphoma; AML=acute myeloid leukemia; MM=multiple myeloma; MDS=myelodysplastic syndrome; CML=chronic myeloid leukemia; N.A.=not applicable.