Table 5. Comparison of meibomian glands between the DE/cGVHD group with systemic cGVHD and the DE/cGVHD group without systemic cGVHD using in vivo confocal microscopy.
| Examinations | DE/cGVHD group with systemic cGVHD (10 eyes, 5 cases) | DE/cGVHD group without systemic cGVHD (7 eyes, 4 cases) | p-value |
|---|---|---|---|
| MGAUD (glands/mm2) |
38.4±30.0 |
85.5±32.3 |
0.0097* |
| MGALD (μm) |
19.3±7.31 |
63.0±14.2 |
< 0.0001* |
| MGASD (μm) |
10.7±4.33 |
27.6±12.0 |
0.0009* |
| Fibrosis (grade) | 1.87±0.23 | 0.71±0.59 | 0.0007‡ |
DE=dry eye; cGVHD=chronic graft-versus-host disease; MGAUD=meibomian gland acinar unit density; MGALD=meibomian gland acinar longest diameter; MGASD=meibomian gland acinar shortest diameter; *=Unpaired t-test; ‡=Mann–Whitney test.