Table 6. Comparison of meibomian glands assessed by in vivo laser confocal microscopy, MG expressibility, meibography and lid margin abnormality between the DE/cGVHD group without systemic cGVHD and non-DE/non-cGVHD group.
| Examinations | DE/cGVHD group without systemic cGVHD (7 eyes, 4 cases) | non-DE/non-cGVHD group (16 eyes, 8 cases) | p-value |
|---|---|---|---|
| MGAUD (glands/mm2) |
85.3±32.3 |
88.8±26.6 |
0.8021 |
| MGALD (μm) |
63.0±14.2 |
60.4±11.8 |
0.65 |
| MGASD (μm) |
27.6±12.0 |
26.6±6.03 |
0.7888 |
| Fibrosis (grade) |
0.71±0.59 |
0.06±0.25 |
0.0016‡ |
| MG expressibility (points) |
2.20±1.10 |
0.75±0.93 |
0.0189‡ |
| Meibography (grade) |
1.14±0.69 |
0.50±0.52 |
0.0399‡ |
| Lid margin (grade) | 2.0±1.41 | 0.38±0.72 | 0.0019‡ |
DE=dry eye; cGVHD=chronic graft-versus-host disease; MGAUD=meibomian gland acinar unit density; MGALD=meibomian gland acinar longest diameter; MGASD=meibomian gland acinar shortest diameter; MG=meibomian gland; ‡=Mann–Whitney test.