Table 6. Mean serum concentrations interleukin-6 (IL-6), high-sensitivity C-reactive protein (hsCRP), and vascular endothelial growth factor (VEGF) in Eales disease (ED) patients at inflammatory stage and healthy controls according to –174G/C genotype.
| Genotype | Patients (n=41) | Controls (n=223) | p value |
|---|---|---|---|
|
IL-6 (pg/ml) | |||
| GG |
45.75 (15.47) |
6.026 (2.558) |
< 0.0001* |
| GC |
13.74 (3.681) |
2.906 (1.383) |
0.0002* |
| CC |
10.68 (2.836) |
2.344 (0.9589) |
0.0022* |
|
hsCRP (mg/l) | |||
| GG |
3.172 (0.5078) |
0.9723 (0.1682) |
< 0.0001* |
| GC |
1.941 (0.09016) |
0.9377 (0.1615) |
0.0002* |
| CC |
1.87 (0.1382) |
0.8475 (0.1065) |
0.0018* |
|
VEGF (pg/ml) | |||
| GG |
324.2 (63.23) |
251.6 (60.66) |
0.0001* |
| GC |
294.9 (50.47) |
219.9 (28.7) |
0.0335* |
| CC | 270.1 (78.81) | 207.1 (45.75) | 0.0397* |
Values are mean (SD) * Significant P value