Table 1.
Baseline characteristics of trial participants
| Placebo group (n=100) | Tranexamic acid group (n=100) | P | |
|---|---|---|---|
| Age (years)* | 64 (7.8) | 64 (7.4) | 0.8 |
| Weight (kg)* | 79 (11.9) | 80 (10.7) | 0.6 |
| Body mass index (kg/m2)* | 26.5 (3.19) | 26.7 (3.23) | 0.6 |
| Body mass index ≥30 kg/m2 | 15 (15) | 15 (15) | 0.9 |
| American Society of Anesthesiologists (ASA) physical status score >2 | 5 (5) | 6 (6) | 0.9 |
| Lee’s revised cardiac risk index >1 | 5 (5) | 8 (8) | 0.5 |
| Hypertension | 37 (37) | 50 (50) | 0.087 |
| Coronary artery disease | 4 (4) | 5 (5) | 0.9 |
| Stroke | 1 (1) | 2 (2) | 0.9 |
| Preoperative systolic arterial pressure (mm Hg)* | 137 (17.4) | 138 (16.9) | 0.6 |
| Preoperative diastolic arterial pressure (mm Hg)* | 79 (9.6) | 80 (10.3) | 0.3 |
| Preoperative treatment | |||
| Antiplatelets | 7 (7) | 17 (17) | 0.0502 |
| Calcium channel blockers | 7 (7) | 20 (20) | 0.01 |
| Diuretics | 17 (17) | 16 (16) | 0.9 |
| β blockers | 9 (9) | 19 (19) | 0.06 |
| Angiotensin-converting enzyme inhibitors | 31 (31) | 37 (37) | 0.4 |
| Hypolipidaemic drugs | 11 (11) | 13 (13) | 0.8 |
| Preoperative Gleason score† | 6 (6-7) | 6 (6-7) | 0.4 |
| Preoperative autologous blood donation | 41 (41) | 35 (35) | 0.5 |
| Nerve-sparing radical prostatectomy | 68 (68) | 72 (72) | 0.6 |
| General anaesthesia | 58 (58) | 52 (52) | 0.4 |
| Spinal anaesthesia | 42 (42) | 48 (48) | 0.4 |
| No of lymph node stations removed† | 4 (4-6) | 4 (4-6) | 0.9 |
Data are number (%) unless stated otherwise.
*Data are mean (standard deviation).
†Data are median (interquartile range).