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. 2011 Oct 18;2:71. doi: 10.3389/fphys.2011.00071

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Copyright © 2011 Wenzel, Held, Palmisano, Teufel, David, Wittenberg and Lang.

This is an open-access article subject to a non-exclusive license between the authors and Frontiers Media SA, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and other Frontiers conditions are complied with.

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Phenotype of Myd88−/− macrophages in cell spreading. BMM from Myd88± and Myd88−/− mice were plated and stimulated as described in Figure 3. Macrophage spreading was analyzed by automated image analysis (left panel) and manual editing (right panel). Shown are mean and SEM from one representative experiment of two performed. LPS (closed symbols), media control (open symbol), Myd88± (circles), Myd88−/− (squares). Statistical significance refers to Myd88± compared to Myd88−/− genotypes. ns = not significant; *** p < 0.0001.