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HIV-nef–positive vascular cell elements have increased giantin. (a) Lung sections from a SHIV-nef–infected macaque with increased giantin in the obliterative vascular lesion probed for HIV-nef and giantin. Scale bar=25 μm. (b) Higher magnifi cation images of the insets depicted in Figure 12a. Scale bar=4μm. Respective 3D intracellular immunoimaging is in ref. 75. (Adapted from ref. 2.)
