Table 1.
Comparison of Presence/Absence of AIA and the Patient Background Factors
| Background | w/o AIA(%) | with AIA(%) | P-value | |
|---|---|---|---|---|
| n = 214 | n = 114 | |||
| Age (yrs) | < 55 | 22(53.7) | 19(46.3) | NS* |
| 55-65 | 97(62.6) | 58(37.4) | ||
| 65 < | 95(72.0) | 37(28.0) | ||
| Age at menarche (yrs) | < 12 | 7(46.7) | 8(53.3) | P = 0.036* |
| 15-Dec | 183(64.7) | 100(35.3) | ||
| 15 < | 22(84.6) | 4(15.4) | ||
| No. of childbirths | 0 | 27(71.1) | 11(28.9) | NS* |
| 2-Jan | 132(63.5) | 76(36.5) | ||
| 2 < | 53(66.3) | 27(33.8) | ||
| Body mass index (kg/m2) | < 25 | 150(68.2) | 70(31.8) | NS* |
| 25-30 | 64(59.3) | 44(40.7) | ||
| Past history of Arthritis | Yes | 48(71.6) | 19(28.4) | NS* |
| No | 166(63.6) | 95(36.4) | ||
| Time since LMP (yrs) | < 5 | 39(54.9) | 32(45.1) | p < 0.001* |
| 10-May | 44(53.7) | 38(46.3) | ||
| 10 < | 131(74.9) | 44(25.1) | ||
| Pre-treatment (HT and/or CT) | No | 134(68.7) | 61(31.3) | NS* |
| Yes | 80(60.2) | 53(39.8) | ||
| Pre-treatment (HT) | No | 166(64.8) | 90(35.2) | NS** |
| Yes | 48(66.7) | 24(33.3) | ||
| With pre-treatment: (Chemo with taxane) | No | 17(51.5) | 16(48.5) | NS* |
| Yes | 27(56.3) | 21(43.8) | ||
| Stage | 0 | 17(60.7) | 11(39.3) | NS** |
| I | 112(62.9) | 66(37.1) | ||
| II | 80(70.8) | 33(29.2) | ||
| III | 5(62.5) | 3(37.5) | ||
| IV | 0 | 1 | ||
| Metastasis to LNs | Yes | 68(63.6) | 39(36.4) | NS* |
| No | 118(65.9) | 61(34.1) | ||
| Nd | 28 | 14 | ||
| ER | + | 204(64.4) | 113(35.6) | NS** |
| - | 10(90.9) | 1(9.1) | ||
AIA: aromatase inhibitor related arthralgia; LMP: last menstrual period;
HT: hormone therapy; CT: chemotherapy; Nd: not detected; ER: estrogen receptor;
w/o: without;
*:Chi-square test; **:Fisher's exact test.