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. 2011 Oct 21;6(10):e25678. doi: 10.1371/journal.pone.0025678

Table 2. Relative optical density (OD) for sOPN bands and OD-based concentration of sOPN in sputum.

Sputum sOPN (µg/ml) Relative OD Relative OD Relative OD p-value
All subjects (N = 33) All subjects (N = 47) Non-asthmatic Subjects (N = 27) Asthmatic Subjects (N = 20)
Polymeric sOPN (≥90 kD) (%) 2.45±2.97 94.2±5.8 96.4±3.2 91.6±1.6 0.009
1.59 [0.58, 2.67] 94.6 [92.7, 98.7] 96.5 [94.6, 99.4] 94.0 [89.0, 97.5]
Monomeric sOPN (50–55 kD) (%) 0.28±0.47 3.2±3.3 2.0±1.8 4.5±4.1 0.025
0.08 [0.00, 0.37] 2.6 [0.7, 4.4] 1.9 [0.0, 2.9] 3.8 [1.6, 6.2]
Cleaved sOPN (25 kD) (%) 0.10±0.15 1.0±1.3 0.7±1.1 1.4±1.5 0.064
0.08 [0.00, 0.08] 0.5 [0.0, 1.5] 0.3 [0.0, 0.9] 1.2 [0.3, 1.6]
Cleaved sOPN (17 kD) (%) 0.11±0.17 1.7±1.9 0.9±1.4 2.6±2.0 0.005
0.03 [0.01, 0.13] 0.9 [0.3, 2.7] 0.6 [0.0, 1.0] 2.7 [0.6, 4.1]

Values are expressed as mean ± SD and median [interquartile range]. Total concentration of sOPN was 3.03±3.41(2.25 [0.80, 3.08]) µg/ml in sputum samples. P-values are for comparisons (Mann-Whitney test) of relative OD of various bands between healthy and asthmatic subjects. Significant p-values are shown in bold.