Table 1. Changes in the cytokine levels in BAL fluid after a single instillation of DEPs (n = 4).
| Control | Day 1 | Day 7 | Day 14 | Day 28 | |
| IL-1 | 11.86±0.92 | 19.84±3.29* | 20.48±4.34* | 16.93±1.63* | 17.28±2.09* |
| TNF-α | 13.25±0.86 | 54.00±4.43** | 33.24±5.57** | 42.18±5.37** | 19.89±1.48* |
| IL-6 | 42.71±1.40 | 115.98±10.73** | 76.92±4.91** | 58.43±1.59* | 56.95±4.22* |
| IL-2 | 19.55±0.70 | 26.52±1.91* | 29.13±5.39* | 27.07±0.93* | 24.92±4.53 |
| IL-12 | 11.18±0.82 | 37.38±7.81* | 116.56±32.82* | 96.40±21.36* | 16.15±1.79* |
| IFN-γ | 13.31±0.46 | 33.42±4.64** | 19.91±3.47* | 18.98±1.14* | 16.00±1.31 |
| IL-4 | 22.24±3.57 | 27.39±4.59 | 26.16±3.10 | 25.07±1.35 | 29.83±3.17 |
| IL-5 | 32.11±1.95 | 36.41±4.03 | 49.79±2.02* | 34.69±3.01 | 36.70±3.54 |
| IL-10 | 54.70±1.53 | 95.72±6.93** | 97.26±6.51** | 80.88±4.86* | 103.20±6.85** |
| IL-13 | 26.92±4.50 | 33.18±8.33* | 56.01±7.74* | 48.76±7.08* | 38.65±3.54* |
| IL-17 | 75.63±0.96 | 106.94±4.49* | 127.70±5.83** | 117.40±3.45** | 119.17±4.29** |
Note: BAL fluid was harvested at each time point and pooled (500 µL per mouse) to 4 test samples per group for further analysis. The level in each group was calculated as mean ± SD of the values measured.
*P<0.05;
**P<0.01.