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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: J Immunol. 2011 Sep 19;187(9):4667–4675. doi: 10.4049/jimmunol.1101949

Figure 2. Competitve bone marrow chimeras reveal defective β-selection in p110γD/D thymocytes.

Figure 2

(A) Example of FACS analysis used to distinguish B6.SJL cell origin based upon expression of the CD45.1 allotypic marker. The gating strategy for CD5loCD69lo DP and CD5hiCD69hi DP thymocytes is also shown. (B) The contribution of B6.SJL (CD45.1+) (■) and WT (B6), p110γD/D or p110γ−/− CD45.1neg cells (□) to thymic T cell subsets, splenic T cells and splenic B cells six weeks after bone marrow reconstitution. The graphs show the mean and SEM from analysis of 10 chimaeric mice.