Figure 4.

Effect of bleomycin treatment on cytokine expression in wild-type and CD69-deficient mice. (A) Cytokine array analyses of BALF 7 d after the instillation of BLM or PBS (sham treatment) in WT or CD69^-/- mice. Cytokines with increased expression levels are boxed. (B) Expression levels of these cytokines in WT (black bars) and CD69^-/- (white bars) mice. Each expression level was normalized by that of the positive control. The stimulation index is the ratio of the expression level of a cytokine in BLM-treated mice to that in sham-treated mice. Results are expressed as the mean (SEM) (n = 4 mice per group). *P < 0.05, **P < 0.01.