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. Author manuscript; available in PMC: 2012 Oct 7.
Published in final edited form as: Biochem Biophys Res Commun. 2011 Sep 8;413(4):588–593. doi: 10.1016/j.bbrc.2011.09.006

Figure 1.

Figure 1

Unsupervised clustering analysis of all metabolites detected by the QTOF-MS(−) mode in 38 subjects’ plasma by a blinded operator. Panel A: Clustering analysis of the metabolites from the entire span of the retention time. The box with black lines indicates potentials of clustering EM subjects from No-EM. Panel B: Clustering analysis of the metabolites from the retention time 0 to 3 minutes. Panel C: Clustering analysis of the metabolites from the retention time 3 to 7 minutes. The box with black lines indicates potentials of clustering EM subjects from No-EM. Panel D: Clustering analysis of the metabolites from the retention time 7 to 10 minutes. Vertical distance is proportional to the relative degrees of clustering. White bar = healthy non-smoking control individual. Grey bar (No-EM) = non-emphysematous cigarette smoking individual. Black bar (EM) = emphysematous cigarette smoking individual.