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. Author manuscript; available in PMC: 2012 Oct 21.
Published in final edited form as: ACS Chem Biol. 2011 Aug 15;6(10):1096–1106. doi: 10.1021/cb200092v

Figure 8.

Figure 8

Functional effects of TR antagonism by SJ-AK and NH-3. A, Growth hormone secretion assay. GH3 cells were cultured with T3 or T3 in combination with SJ-AK or SMT for 24 hours. Cell culture media was sampled and assayed for the presence of growth hormone using a sandwich ELISA kit. Growth hormone secretion as a percentage of DMSO control is plotted. * indicates p < 0.05; ** indicates p < 0.01. B, Cell growth assay. GH3 cells seeded were treated as indicated and kept in culture for 96 hours. At that point, cell viability was assessed using a luminescent measure of ATP content. *** indicates p < 0.005.