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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2011 Apr 29;17(11):1662–1672. doi: 10.1016/j.bbmt.2011.04.008

Figure 3. KIR2DS2 and KIR2DS4 expression by mRNA-based Q-PCR in HCT subjects.

Figure 3

The samples from non-viremic (NV) subjects are in clear symbol and samples from viremic subjects in black. KIR2DS2 is represented in circles and KIR2DS4 in squares. A mean value was reported per patient and the KIR expression values were reported only if the corresponding donor KIR genotype was present. The copy number for each subject was normalized to 1×106 β-actin copies and the median copy number is shown at the top of each group. A Mann-Whitney (MW) test was performed to establish p values between the NV and Viremic groups. Panel A) shows the overall expression of either KIR 2DS2 or KIR2DS4 in both groups NV and V; B) differentiates between the expression of KIR2DS4 and the deletion mutant KIR2DS4d and C) shows the results for recipients receiving both genotypes together from donor cells. The null-expressers are represented as log 100=1 on the y axis.