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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Oral Oncol. 2011 Aug 12;47(11):1011–1016. doi: 10.1016/j.oraloncology.2011.07.012

Figure 4. hnRNP G mutations in hnRNP G-positive HOSCC.

Figure 4

A. PCR-SSCP analysis of exon 2 (left) and exon 9 (right) of the hnRNP G gene. Abnormal band patterns were noted in the exon 2 of case 5 and in the exon 9 of case 37 and 41. B. DNA sequencing analysis of the hnRNP G gene of case 5 and 37. A missense mutation from Gly (GGC) to Asp (GAC) at codon 29 in exon 2 was found in case 5. Identical mutations, one base pair C deletion at the 1st nucleotide in codon 368 and a base pair substitution from C to T at the 1st nucleotide in codon 369 were found in case 37. Identical C deletion was also detected from case 41 (data not shown).