Table 2.

Clinicopathological parameters and hnRNP G status in the specimens

Pathologic category	Age/sex	Degree of differentiation	hnRNP G status
			Protein expressiona	Genetic alteration
Normal (n=12)
1	M/39		+++	wtb
2	M/57		+++	wt
3	F/25		+++	ndc
4	M/39		+++	nd
5	F/65		+++	nd
6	F/37		+++	wt
7	F/44		+++	wt
8	M/70		+++	wt
9	F/65		+++	wt
10	M/50		+++	wt
11	M/65		+++	wt
12	F/59		+++	wt
Keratotic white lesion (n=19)
1	M/73		+++	wt
2	F/25		+++	nd
3	F/76		+++	nd
4	M/71		+	wt
5	M/70		+++	nd
6	F/56		+	nd
7	M/66		++	nd
8	M/61		+++	wt
9	M/29		++	nd
10	M/41		++	nd
11	F/55		++	nd
12	M/56		++	nd
13	M/54		++	nd
14	F/54		+++	nd
15	F/67		++	nd
16	F/65		+++	nd
17	F/46		+++	nd
18	F/63		+++	wt
19	F/67		+++	nd
Dysplasia (n=12)
1	F/83	Mild	+++	wt
2	M/53	Moderate -severe	+	nd
3	M/72	Mild	+	nd
4	M/53	Mild	−	nd
5	M/53	Mild	−	wt
6	M/77	Mild	+	nd
7	M/54	Mild	−	del.d exon 3, 4
8	nae/na	Moderate -severe	+	nd
9	F/70	Moderate -severe	−	nd
10	M/54	Moderate -severe	++	wt
11	M/53	Severe	−	wt
12	M/38	Severe	+	wt
Squamous cell carcinomas (n=41)
1	F/82	Well	−	del. entire exon
2	M/75	Well	−	del. exon 3,4,5,6,7,9
3	M/71	Well	−	del. entire exon
4	M/71	Well	−	nd
5	F/nk	Moderate	++	missense mutation
6	F/76	Moderate-well	+	wt
7	M/73	Moderate	++	wt
8	F/79	Moderate	−	del. exon 2,3,4
9	M/70	Moderate	−	nd
10	M/67	Moderate	−	del. exon 7,8
11	M/70	Poor	−	del. exon 8,9
12	M/81	Well	+	wt
13	M/53	Well	+	wt
14	M/71	Moderate	−	del. exon 3,6,7
15	F/53	Moderate	−	del. entire exon
16	M/55	Poor	−	del. exon 3,7,8
17	F/78	Moderate	−	del. entire exon
18	M/53	Poor	++	wt
19	M/65	Well	+	wt
20	M/66	Poor	++	wt
21	M/62	Well	+	del. exon 6,8
22	F/52	Well	−	del. exon 4,9
23	F/84	Moderate	−	del. exon 9
24	M/73	Moderate-poor	−	wt
25	M/63	Well	−	wt
26	F/86	Moderate	−	nd
27	F/61	Moderate	+	del. exon 3,6,8
28	M/72	Well	+	del. exon 4,6,
29	M/70	Well-moderate	++	wt
30	F/49	Moderate	++	wt
31	M/69	Well-moderate	+	wt
32	M/70	Moderate	−	wt
33	F/53	Moderate	+	del. exon 3,4,6,8
34	M/88	Moderate	−	del. entire exon
35	M/94	Well	−	del. exon 2,3,4,5,6,7
36	M/59	Poor	+++	wt
37	F/65	Moderate	++	frameshift & missense
38	M/67	Moderate	+	wt
39	M/50	Moderate	+	wt
40	M/66	Moderate	+++	wt
41	M/43	Moderate	+	frameshift & missense

^aThe level of hnRNP G immunostaining per each specimen was scored as negative (−), weak (+), moderate (++), or strong (+++) by two independent observations.

^bwild-type

^cnot determined

^ddeleted

^enot available